We employed massively parallel sequencing of all X-chromosome exons in the index males. This was confirmed by in vitro studies, which showed that the identified variants not only impair ACTG2 polymerization, but also contribute to reduced cell contractility. Seasonal variation had an effect on 15 proteins and month number of sun hours affected 36 proteins and explained up to 4. Cultured under xeno-free and defined conditions. Samhällsvetenskap 3 Utbildningsvetenskap 3 Didaktik 3. Occupational hygienists estimated the average annual intensity of exposure to solvents, pesticides and metals, iron, copper, manganeseblind to disease status.
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Exome sequencing was performed to identify the underlying gene defect.
A further set of patients, from the same trial, was used for replication. Linköpings universitet, Institutionen för fysik, kemi och biologi. Angiotensin-converting enzyme inhibitor-induced cough is potentially associated with genes that are independent of bradykinin pathways. Vox Sanguinis International Forum on application of fetal blood grouping: Neurons in other regions of the spinal cord, e.